Size 00 HPMC Capsule

Size 00 HPMC Capsule
HPMC capsules have a lower overall moisture content than do gelatin capsules, which can present a major benefit for protecting the integrity of nutraceutical products.
HPMC capsules have a moisture content ranging from 3 to 8 percent, making them an attractive option for hygroscopic and moisture-sensitive formulations. This also makes them less susceptible to low-humidity-related adverse reactions, since the relative humidity in the surrounding environment would need to be far lower to exact any significant toll.
Since gelatin capsules have a comparatively higher moisture content—typically 13 to 16 percent—with water acting as a plasticizer (essentially, a molding agent), when they are stored at relative humidity under 40 percent they lose water and become less flexible, yielding brittleness. A similarly resulting vulnerability can occur with moisture-sensitive products. The most common method of protecting such formulas is using desiccants. Of course, this can artificially create the same scenario in which a drier external environment pulls water from capsules, leaving them brittle.
But HPMC capsules have a moisture content ranging from 3 to 8 percent, making them an attractive option for hygroscopic and moisture-sensitive formulations. This also makes them less susceptible to low-humidity-related adverse reactions, since the relative humidity in the surrounding environment would need to be far lower to exact any significant toll.

Advantages of Size 00 HPMC Capsule


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